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irregular menstrual bleeding

Practice targeted AMC-style multiple-choice questions on irregular menstrual bleeding.

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A 45-year-old woman presents to her GP with a 6-month history of irregular menstrual cycles and hot flashes. She also reports mood swings and difficulty sleeping. Her last menstrual period was 3 months ago. What is the most likely diagnosis?

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A 32-year-old woman presents to the clinic with a 6-month history of irregular menstrual cycles and excessive facial hair growth. She has gained 5 kg over the past year and reports difficulty losing weight despite regular exercise. On examination, she has acne and hirsutism. Her BMI is 28 kg/m². Blood tests reveal elevated testosterone levels and normal TSH and prolactin levels. What is the most likely diagnosis?

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A 52-year-old woman presents to her general practitioner with concerns about irregular menstrual bleeding over the past six months. She has a history of obesity, with a BMI of 32 kg/m², and was recently diagnosed with type 2 diabetes mellitus. She reports that her periods have been irregular for the past few years, often skipping months. She is not currently on any hormone replacement therapy. On examination, she has no signs of hirsutism or virilization. Her blood pressure is 140/85 mmHg, and her fasting blood glucose level is 8.5 mmol/L. Which of the following groups of women is most at risk for developing endometrial hyperplasia?

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